Domestic Box Office Results for 2021 Week 48 (3-Day Nov 26 - Nov 28)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| - | Encanto | PG | Walt Disney Studios Motion Pictures | $27,206,494 | - | 3,980 | 3,980 | $6,836 | $40,567,273 | 2 |
| - | Ghostbusters: Afterlife | - | Sony Pictures Entertainment (SPE) | $24,200,387 | -45.0% | 4,315 | - | $5,608 | $87,514,898 | 2 |
| - | House of Gucci | R | United Artists Releasing | $14,423,794 | - | 3,477 | 3,477 | $4,148 | $22,014,298 | 2 |
| - | Eternals | PG-13 | Walt Disney Studios Motion Pictures | $7,925,905 | -28.5% | 3,165 | -890 | $2,504 | $150,736,150 | 4 |
| - | Resident Evil: Welcome to Raccoon City | R | Screen Gems | $5,319,280 | - | 2,803 | 2,803 | $1,898 | $8,850,619 | 2 |
| - | Clifford the Big Red Dog | PG | Paramount Pictures | $5,007,631 | -38.3% | 3,292 | -336 | $1,521 | $43,016,850 | 4 |
| - | King Richard | PG-13 | Warner Bros. | $3,272,353 | -39.5% | 3,302 | - | $991 | $11,345,895 | 2 |
| - | Dune | - | Warner Bros. | $2,080,111 | -34.5% | 1,266 | -1,201 | $1,643 | $88,380,853 | 6 |
| - | No Time to Die | - | Metro-Goldwyn-Mayer (MGM) | $1,707,256 | -38.3% | 1,342 | -1,065 | $1,272 | $158,081,024 | 8 |
| - | Venom: Let There Be Carnage | PG-13 | Sony Pictures Entertainment (SPE) | $1,581,315 | -45.7% | 1,537 | -1,001 | $1,029 | $209,518,406 | 9 |
| - | Belfast | PG-13 | Focus Features | $958,770 | 1.4% | 1,128 | 544 | $850 | $4,968,605 | 3 |
| - | The French Dispatch | R | Searchlight Pictures | $627,020 | -37.3% | 397 | -408 | $1,579 | $14,495,812 | 6 |
| - | Licorice Pizza | R | United Artists Releasing | $345,157 | - | 4 | - | $86,289 | $345,157 | 1 |
| - | C’mon C’mon | R | A24 | $310,028 | 130.6% | 102 | 97 | $3,039 | $544,996 | 2 |
| - | Spencer | R | NEON | $211,917 | -70.1% | 346 | -608 | $612 | $6,641,946 | 4 |
| - | For the Love of Money | R | Freestyle Releasing | $211,286 | - | 519 | 519 | $407 | $285,955 | 2 |
| - | Ron’s Gone Wrong | PG | 20th Century Studios | $202,276 | -78.5% | 450 | -1,070 | $450 | $22,751,410 | 6 |
| - | Aline | PG-13 | Roadside Attractions | $164,087 | - | 70 | - | $2,344 | $164,087 | 1 |
| - | L’Arracheuse de temps | - | Entertainment One | $107,827 | -42.9% | 68 | - | $1,586 | $409,199 | 2 |
| - | Julia | PG-13 | Sony Pictures Classics | $100,402 | 137.2% | 288 | 241 | $349 | $226,333 | 3 |
| - | Sooryavanshi | TV-14 | Reliance Entertainment | $80,452 | -67.1% | 59 | -156 | $1,364 | $3,547,776 | 4 |
| - | The Battle at Lake Changjin | Other | CMC Pictures | $61,161 | -42.2% | 16 | -4 | $3,823 | $243,874 | 2 |
| - | My Hero Academia: World Heroes’ Mission | PG-13 | FUNimation Entertainment | $61,033 | -77.3% | 67 | -315 | $911 | $12,194,106 | 5 |
| - | Anita | - | CMC Pictures | $59,297 | -42.3% | 12 | -3 | $4,941 | $427,681 | 3 |
| - | Antlers | R | Searchlight Pictures | $57,857 | -84.4% | 177 | -513 | $327 | $10,507,944 | 5 |
| - | Last Night in Soho | - | Focus Features | $53,255 | -77.3% | 110 | -279 | $484 | $10,107,485 | 5 |
| - | The Addams Family 2 | PG | United Artists Releasing | $41,444 | -75.4% | 107 | -400 | $387 | $56,434,328 | 9 |
| - | India Sweets and Spices | PG-13 | Bleecker Street Media | $29,663 | -82.6% | 121 | -222 | $245 | $266,647 | 2 |
| - | The Last Duel | - | 20th Century Studios | $25,052 | -41.0% | 130 | -35 | $193 | $10,846,869 | 7 |
| - | Halloween Kills | - | Universal Pictures | $18,770 | -91.2% | 165 | -462 | $114 | $91,971,790 | 7 |
| - | Shang-Chi and the Legend of the Ten Rings | PG-13 | Walt Disney Studios Motion Pictures | $14,849 | -69.7% | 65 | -55 | $228 | $224,537,817 | 13 |
| - | Drive My Car | Other | Janus Films | $13,775 | - | 2 | - | $6,888 | $13,775 | 1 |
| - | Free Guy | - | 20th Century Studios | $11,802 | -34.0% | 45 | -20 | $262 | $121,623,717 | 16 |
| - | Bad Luck Banging or Loony Porn | Other | Magnolia Pictures | $7,609 | -0.8% | 5 | 3 | $1,522 | $19,696 | 2 |
| - | Kurt Vonnegut: Unstuck in Time | Other | IFC Films | $6,129 | -77.7% | 30 | -39 | $204 | $47,992 | 2 |
| - | Breathless (2021 Re-release) | TV-14 | Rialto Pictures | $3,443 | 372.9% | 2 | 1 | $1,722 | $43,893 | 9 |
| - | Writing with Fire | Other | Music Box Films | $3,423 | - | 4 | - | $856 | $3,423 | 1 |
| - | The Rescue | PG | Greenwich Entertainment | $3,340 | -66.8% | 14 | -11 | $239 | $1,051,887 | 8 |
| - | Une révision | - | Entertainment One | $3,185 | -78.0% | 8 | -30 | $398 | $151,531 | 4 |
| - | What Do We See When We Look at the Sky? | - | MUBI | $1,270 | -39.4% | 4 | 2 | $318 | $11,572 | 3 |
| - | The Feast | - | IFC Films | $1,157 | -68.0% | 7 | -15 | $165 | $7,172 | 2 |
| - | The Incredibly True Adventure of Two Girls in Love (2021 Re-release) | R | Strand Releasing | $1,066 | - | 1 | 1 | $1,066 | $2,868 | 2 |
| - | Below the Fold | - | Independent | $875 | -67.3% | 1 | - | $875 | $3,550 | 2 |
| - | I Need You Dead! | Other | Independent | $790 | - | 1 | - | $790 | $790 | 1 |
| - | Azor | - | MUBI | $636 | 148.4% | 1 | -1 | $636 | $47,570 | 9 |
| - | Cicada | Other | Strand Releasing | $395 | -72.7% | 1 | -1 | $395 | $13,210 | 5 |
| - | Wife of a Spy | - | Kino Lorber | $322 | -39.9% | 1 | - | $322 | $67,850 | 11 |
| - | Luzzu | - | Kino Lorber | $257 | 38.2% | 2 | - | $129 | $16,938 | 7 |
| - | I’m Your Man | R | Bleecker Street Media | $225 | -70.5% | 3 | - | $75 | $275,155 | 10 |
| - | I Was a Simple Man | - | Strand Releasing | $169 | -97.8% | 1 | -5 | $169 | $10,386 | 2 |
| - | Shiva Baby | TV-MA | Utopia | $143 | -8.3% | 1 | -1 | $143 | $158,571 | 25 |
