Domestic Box Office Results for 2021 Week 38 (3-Day Sep 17 - Sep 19)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| - | Shang-Chi and the Legend of the Ten Rings | PG-13 | Walt Disney Studios Motion Pictures | $21,670,751 | -37.6% | 4,070 | -230 | $5,325 | $176,864,306 | 3 |
| - | Free Guy | - | 20th Century Studios | $5,086,435 | -8.8% | 3,288 | -377 | $1,547 | $108,462,465 | 6 |
| - | Cry Macho | PG-13 | Warner Bros. | $4,426,161 | - | 3,967 | - | $1,116 | $4,426,161 | 1 |
| - | Candyman | R | Universal Pictures | $3,524,205 | -26.0% | 2,820 | -459 | $1,250 | $53,192,695 | 4 |
| - | Malignant | R | Warner Bros. | $2,716,557 | -50.0% | 3,501 | 16 | $776 | $9,840,084 | 2 |
| - | Copshop | R | Open Road Films | $2,315,638 | - | 3,005 | - | $771 | $2,315,638 | 1 |
| - | Jungle Cruise | PG-13 | Walt Disney Studios Motion Pictures | $2,077,076 | -10.8% | 2,265 | -500 | $917 | $112,571,412 | 8 |
| - | PAW Patrol: The Movie | G | Paramount Pictures | $1,722,105 | -25.1% | 2,269 | -551 | $759 | $37,115,602 | 5 |
| - | Don’t Breathe 2 | R | Screen Gems | $671,096 | -42.0% | 1,003 | -705 | $669 | $31,344,224 | 6 |
| - | The Eyes of Tammy Faye | PG-13 | Searchlight Pictures | $652,358 | - | 450 | - | $1,450 | $652,358 | 1 |
| - | The Card Counter | R | Focus Features | $418,560 | -59.7% | 584 | 4 | $717 | $1,892,950 | 2 |
| - | Show Me the Father | PG | Affirm Films | $370,779 | -47.0% | 1,073 | - | $346 | $1,380,902 | 2 |
| - | Blue Bayou | R | Focus Features | $329,840 | - | 477 | - | $691 | $329,840 | 1 |
| - | Respect | PG-13 | Metro-Goldwyn-Mayer (MGM) | $282,733 | -44.7% | 807 | -500 | $350 | $23,755,195 | 6 |
| - | Ghost in the Shell (2021 4K Remaster) | Other | Lionsgate | $220,389 | - | 124 | - | $1,777 | $220,389 | 1 |
| - | After We Fell | R | Vertical Entertainment | $185,805 | -56.4% | 246 | - | $755 | $761,833 | 2 |
| - | Black Widow (Streaming - PVOD) | - | Walt Disney Studios Motion Pictures | $183,213 | -35.3% | 325 | -185 | $564 | $183,385,207 | 11 |
| - | Old | PG-13 | Universal Pictures | $180,275 | -26.4% | 474 | -109 | $380 | $47,990,865 | 9 |
| - | The Suicide Squad | - | Warner Bros. | $164,608 | -57.7% | 416 | -415 | $396 | $55,570,323 | 7 |
| - | The Alpinist | PG-13 | Roadside Attractions | $138,390 | -56.6% | 245 | 73 | $565 | $558,996 | 2 |
| - | Promare | TV-PG | GKIDS | $118,880 | - | 635 | 635 | $187 | $2,529,082 | 19 |
| - | The Night House | R | Searchlight Pictures | $96,492 | -47.0% | 210 | -300 | $459 | $6,931,014 | 5 |
| - | Space Jam: A New Legacy | PG | Warner Bros. | $93,702 | -9.1% | 181 | -49 | $518 | $75,466,910 | 10 |
| - | The Protégé | R | Lionsgate | $53,552 | -58.0% | 153 | -241 | $350 | $7,419,867 | 5 |
| - | The Boss Baby 2: Family Business | PG | Universal Pictures | $52,745 | -25.8% | 396 | -87 | $133 | $57,174,245 | 12 |
| - | Little Eggs: An African Rescue | Other | Pantelion Films | $37,609 | -34.3% | 71 | -44 | $530 | $887,321 | 4 |
| - | F9: The Fast Saga | PG-13 | Universal Pictures | $36,880 | 16.1% | 305 | -33 | $121 | $172,970,725 | 13 |
| - | The Lost Leonardo | PG-13 | Sony Pictures Classics | $31,407 | -61.5% | 139 | -78 | $226 | $381,044 | 6 |
| - | The Forever Purge | R | Universal Pictures | $20,450 | -40.6% | 175 | -7 | $117 | $44,525,465 | 12 |
| - | The Nowhere Inn | Other | IFC Films | $19,054 | - | 46 | - | $414 | $19,054 | 1 |
| - | Language Lessons | - | Shout! Factory | $11,040 | -58.0% | 31 | -13 | $356 | $49,539 | 2 |
| - | Tango Shalom | PG-13 | Vision Films | $10,876 | -51.0% | 27 | -2 | $403 | $69,564 | 3 |
| - | Reminiscence | PG-13 | Warner Bros. | $8,709 | -16.0% | 35 | -35 | $249 | $3,890,043 | 5 |
| - | Azor | - | MUBI | $7,779 | 23.1% | 52 | 50 | $150 | $18,297 | 2 |
| - | Raging Fire | Other | Well Go USA Entertainment | $7,773 | - | 4 | 4 | $1,943 | $255,657 | 6 |
| - | Wife of a Spy | - | Kino Lorber | $7,162 | - | 1 | - | $7,162 | $7,162 | 1 |
| - | Flag Day | R | United Artists Releasing | $5,873 | -87.0% | 35 | -132 | $168 | $416,454 | 5 |
| - | Fire Music | - | Submarine Deluxe | $5,300 | - | 3 | - | $1,767 | $5,300 | 1 |
| - | Mogul Mowgli | - | Strand Releasing | $5,171 | -63.0% | 14 | -17 | $369 | $39,286 | 3 |
| - | Nine Days | R | Sony Pictures Classics | $4,397 | -34.3% | 11 | -9 | $400 | $682,667 | 8 |
| - | 12 Mighty Orphans | PG-13 | Sony Pictures Entertainment (SPE) | $3,886 | -56.8% | 22 | -11 | $177 | $3,679,832 | 15 |
| - | On Broadway | - | Kino Lorber | $3,826 | -58.8% | 18 | -38 | $213 | $66,290 | 5 |
| - | Who You Think I Am | - | Cohen Media Group | $3,587 | -54.5% | 10 | -8 | $359 | $33,237 | 3 |
| - | Little Girl | - | Music Box Films | $2,742 | - | 3 | - | $914 | $2,742 | 1 |
| - | Cryptozoo | Other | Magnolia Pictures | $1,911 | 310.1% | 6 | 2 | $319 | $32,338 | 5 |
| - | The Swimming Pool (2021 Re-release) | Other | Rialto Pictures | $1,824 | -60.1% | 9 | 2 | $203 | $210,626 | 19 |
| - | Baking Up Love | - | Independent | $1,371 | - | - | - | $1,371 | $6,286 | 3 |
| - | Swan Song | R | Magnolia Pictures | $1,316 | -52.9% | 4 | -11 | $329 | $122,855 | 7 |
| - | Dating & New York | PG-13 | IFC Films | $1,078 | -92.2% | 12 | -26 | $90 | $20,738 | 2 |
| - | The Ladykillers (2021 Re-release) | Other | Rialto Pictures | $826 | 104.5% | 1 | - | $826 | $23,038 | 9 |
| - | Together | R | Universal Pictures | $821 | -58.2% | 14 | -230 | $59 | $213,907 | 4 |
| - | Yakuza Princess | R | Magnolia Pictures | $768 | -38.0% | 2 | -3 | $384 | $16,704 | 3 |
| - | Ema | R | Music Box Films | $120 | -78.1% | 1 | -1 | $120 | $51,676 | 6 |
| - | Le Cercle Rouge (re) (2021 Re-release) | Other | Rialto Pictures | $90 | -68.3% | 1 | - | $90 | $62,675 | 12 |
