Domestic Box Office Results for 2021 Week 23 (3-Day Jun 4 - Jun 6)
| Rank | Title | Rating | Distributor | Total Weekend | +-LW | Locations | +-LW | Avg. Per Location | Total To-Date | Weeks |
|---|---|---|---|---|---|---|---|---|---|---|
| - | The Conjuring: The Devil Made Me Do It | R | Warner Bros. | $24,104,332 | - | 3,102 | - | $7,771 | $24,104,332 | 1 |
| - | A Quiet Place Part II | PG-13 | Paramount Pictures | $19,266,977 | -59.5% | 3,744 | 18 | $5,146 | $88,377,962 | 2 |
| - | Cruella | PG-13 | Walt Disney Studios Motion Pictures | $11,001,929 | -48.8% | 3,922 | 30 | $2,805 | $43,443,602 | 2 |
| - | Spirit Untamed | PG | Universal Pictures | $6,101,050 | - | 3,211 | - | $1,900 | $6,101,050 | 1 |
| - | Raya and the Last Dragon | PG | Walt Disney Studios Motion Pictures | $1,282,536 | -45.2% | 1,504 | -511 | $853 | $53,504,682 | 14 |
| - | Wrath of Man | R | United Artists Releasing | $1,266,113 | -41.8% | 2,607 | - | $486 | $24,669,827 | 5 |
| - | Spiral | Other | Lionsgate | $893,870 | -59.7% | 1,983 | -658 | $451 | $21,802,214 | 4 |
| - | Godzilla vs. Kong | PG-13 | Warner Bros. | $521,106 | -41.0% | 1,390 | -425 | $375 | $97,858,385 | 11 |
| - | Demon Slayer: Kimetsu no Yaiba – The Movie: Mugen Train | R | FUNimation Entertainment | $457,246 | -47.2% | 562 | -569 | $814 | $47,710,188 | 7 |
| - | Dream Horse | PG | Bleecker Street Media | $258,021 | -59.9% | 648 | -636 | $398 | $2,360,309 | 3 |
| - | Witnesses | PG | Purdie Distribution | $134,490 | - | 90 | - | $1,494 | $134,490 | 1 |
| - | Those Who Wish Me Dead | R | Warner Bros. | $108,275 | -81.7% | 748 | -1,057 | $145 | $6,658,027 | 4 |
| - | Tom & Jerry | PG | Warner Bros. | $90,247 | -28.1% | 1,121 | - | $81 | $45,782,025 | 15 |
| - | Finding You | PG | Roadside Attractions | $70,662 | -72.6% | 550 | -389 | $128 | $2,665,082 | 4 |
| - | Mortal Kombat | - | Warner Bros. | $69,043 | -74.1% | 118 | -842 | $585 | $37,187,718 | 7 |
| - | The Croods: A New Age | PG | Universal Pictures | $56,285 | -2.0% | 889 | -37 | $63 | $58,387,180 | 29 |
| - | Nobody | R | Universal Pictures | $44,350 | -59.3% | 417 | -249 | $106 | $26,087,035 | 11 |
| - | The Unholy | PG-13 | Screen Gems | $35,050 | -61.6% | 68 | -235 | $515 | $15,510,002 | 10 |
| - | The Dry | R | IFC Films | $29,741 | -52.4% | 58 | -68 | $513 | $286,456 | 3 |
| - | Here Today | PG-13 | Stage 6 Films | $27,733 | -60.6% | 85 | -236 | $326 | $2,748,629 | 5 |
| - | Undine | Other | IFC Films | $27,065 | - | 56 | - | $483 | $27,065 | 1 |
| - | The Truffle Hunters | PG-13 | Sony Pictures Classics | $18,978 | -18.5% | 33 | -18 | $575 | $340,596 | 9 |
| - | Gully | R | Vertical Entertainment | $14,425 | - | 100 | - | $144 | $14,425 | 1 |
| - | Hero Mode | PG | Blue Fox Entertainment | $11,843 | - | 46 | - | $257 | $11,843 | 1 |
| - | The Courier | PG-13 | Roadside Attractions | $8,275 | -53.8% | 20 | -40 | $414 | $6,589,963 | 12 |
| - | New Order | R | NEON | $7,628 | -85.7% | 15 | -171 | $509 | $300,616 | 3 |
| - | Riders of Justice | Other | Magnolia Pictures | $7,350 | -43.4% | 15 | -1 | $490 | $63,582 | 4 |
| - | French Exit | R | Sony Pictures Classics | $7,279 | -24.2% | 6 | -1 | $1,213 | $721,148 | 10 |
| - | All Light, Everywhere | Other | Super LTD | $5,376 | - | 2 | - | $2,688 | $5,376 | 1 |
| - | The Father | PG-13 | Sony Pictures Classics | $5,370 | -32.2% | 16 | -2 | $336 | $2,061,368 | 13 |
| - | The Ladykillers (2021 Re-release) | Other | Rialto Pictures | $5,038 | - | 1 | - | $5,038 | $5,038 | 1 |
| - | The Swimming Pool (2021 Re-release) | Other | Rialto Pictures | $4,846 | -38.1% | 7 | 2 | $692 | $48,841 | 4 |
| - | The Paper Tigers | PG-13 | Well Go USA Entertainment | $4,798 | 4.9% | 10 | 4 | $480 | $100,203 | 5 |
| - | Together Together | R | Bleecker Street Media | $4,679 | -38.3% | 15 | -12 | $312 | $1,425,315 | 7 |
| - | The Girl Who Believes in Miracles | PG | Atlas Distribution Company | $4,465 | -50.4% | 25 | -50 | $179 | $3,153,040 | 10 |
| - | The Perfect Candidate | - | Music Box Films | $4,274 | 10.8% | 17 | 2 | $251 | $20,638 | 4 |
| - | The Killing of Two Lovers | R | NEON | $2,854 | -58.5% | 14 | -8 | $204 | $71,162 | 4 |
| - | The War with Grandpa | PG | 101 Studios | $1,438 | -31.8% | 25 | -10 | $58 | $21,272,853 | 35 |
| - | About Endlessness | - | Magnolia Pictures | $1,351 | -48.1% | 3 | -1 | $450 | $38,798 | 6 |
| - | Cliff Walkers | - | CMC Pictures | $1,180 | -51.7% | 5 | 1 | $236 | $152,972 | 6 |
| - | The Djinn | R | IFC Films | $634 | -93.6% | 5 | -16 | $127 | $124,644 | 4 |
| - | Mainstream | R | IFC Films | $424 | -34.0% | 2 | -1 | $212 | $35,481 | 5 |
| - | Mission Stories | - | Excel Entertainment | $284 | -78.4% | 4 | -6 | $71 | $85,000 | 5 |
| - | The Incredible 25th Year of Mitzi Bearclaw | - | Indican Pictures | $94 | -77.7% | 1 | - | $94 | $7,750 | 10 |
| - | Ghost Master | - | Indican Pictures | $87 | -65.2% | 1 | - | $87 | $6,217 | 4 |
